NIPE

Based on the results obtained from the ANI technology on the monitoring of non-communicating adults patients, 3 more years of research and development were necessary to give birth to the NIPE index
(Newborn Infant Parasympathetic Evaluation). The NIPE technology enables the evaluation of the parasympathetic part of the Autonomous Nervous System of newborns, from premature to the age of 2 years,
from the electrocardiogram provided by the multi parametric monitor.

The FIRST comfort assessment monitoring system for neonates

The NIPE technology enables an objective and continuous measurement of the parasympathetic component of the Autonomous Nervous System in babies and young infants. The unique technology has efficacy proven to work with extremely premature babies from around 26 weeks gestation through to infants up to two years of age and is based on the electrocardiogram taken from the patient monitor in use.

The level of parasympathetic tone is correlated to the infant’s discomfort and wellbeing, giving an objective measure.

Monitor NIPE

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Testimonials

Our technologies are used by top physicians around the world in both OR and ICU settings

Dr. Héctor Boix

Thanks to NIPE we have an objective parameter to assess stress in our neonatal ICUs

Dr. Héctor Boix

Neonatal Researcher at Hospital Vall d’Hebron Barcelona

Dr. Francisco Reinoso Barbero

NIPE is an excellent intraoperative tool for pediatric anesthesiologists who assist neonates and infants. NIPE device allow us not only to confirm the efficacy of regional blocks but also titrate analgesic drugs like opiates, dexmedetomidine while tailoring hypnotic agents, achieving a very early and comfortable extubation in these very young patients.

Dr. Francisco Reinoso Barbero

Chief of Anesthesia of Anesthesiology Department Hosptal La Paz, Madrid

Scientific Evidences

Clinical studies

  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “MDoloris capte les douleurs muettes” – Les Echos 121 / LEARN MORE
  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “C’est la première fois qu’on mesure la douleur” – La Voix du Nord/ LEARN MORE

Case reports

  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “MDoloris capte les douleurs muettes” – Les Echos 121 / LEARN MORE
  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “C’est la première fois qu’on mesure la douleur” – La Voix du Nord/ LEARN MORE
  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “MDoloris capte les douleurs muettes” – Les Echos 121 / LEARN MORE
  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “C’est la première fois qu’on mesure la douleur” – La Voix du Nord/ LEARN MORE

Publications

  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “MDoloris capte les douleurs muettes” – Les Echos 121 / LEARN MORE
  • Obtention du prix “Entrepreneur de l’année 2014, Born Global” – l’Express / LEARN MORE
  • “C’est la première fois qu’on mesure la douleur” – La Voix du Nord/ LEARN MORE

Videos

Use of the NIPE technology on neonates – ANI technology

NIPE on 18-month-old toddler