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SEDAR Congress 2023, Seville, Spain


Euroanaesthesia 2023, Glasgow, Scotland


ASA, Philadelphia, PA

When dexmedetomidine is administered in a patient

When dexmedetomidine is administered in a patient under general anesthesia the effect is reflected in the ANI monitor, which shows an increase in the ANI value, indicating that the patient is experiencing a higher level of analgesia. This proves that what is important is the control of the autonomic nervous system.    
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Nociception associated with pain/distress in young children

An interesting new Clinical Study on nociception associated with pain/distress in young children sedated for dental treatment. The study demonstrates the correlation of ANI with FLACC and VAS scales and how it is a precise continuous way to assess pain in pediatric patients. The ANI technology constantly proves its validation to guide physicians in controlling… View Article
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New publication with focus on pediatrics

A new publication giving an overview of the most up-to-date information available in the literature on current nociception monitors available in clinical practice, with a particular focus on pediatrics. The paper concludes that intraoperative nociception monitors such as ANI and NIPE appear to be the most helpful parameters in guiding anesthetic management, and their use should… View Article
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Pain Monitoring for those who cannot self-report

Read the latest article on “Pain Monitoring for those who cannot self-report” published in Pharmaceutical Manufacturing and Packing Sourcer and learn how our technologies are changing the future of pain monitoring. *This article is taken from Pharmaceutical Manufacturing and Packing Sourcer February 2023, pages 26-28. © Samedan Ltd. Read the full journal here:    
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How ANI reacts- BP doesn’t always predict nociception.

As shown in this publication, when blood pressure is high during some surgical procedures, it does not mean that the patient needs more Fentanyl.As we witness in this case, the ANI value is high reflecting that the patient is comfortable despite the patient’s BP being high. A bolus of urapidil was added to lower BP, but the… View Article
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How ANI reacts- On OFA and bolus of Ketamine

Another OFA case by Dr. Ricardo Villamarin shows how ANI can react and detect nociception while the patient is undergoing a laparoscopic prostatectomy. When the doctor induces the patient with a ketamine bolus and it starts its effect, the ANI value increases reflecting the drug’s effect which makes the doctor able to stabilize the patient’s condition and… View Article
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Detection of nociception and labetalol bolus shown in PTA

MDoloris Medical Systems designed the PTA technology to monitor animals’ comfort during surgery by measuring the parasympathetic tone of their autonomic nervous system, to control nociception and anticipate analgesia needs. Here we see when an animal is under surgical stress during a procedure, the PTA value decreases. When the patient is given Labetalol bolus, that value increases, exhibiting the drug’s… View Article
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ANI shows the analgesic effect of metoprolol

In 1952, Dr. Cecil Gray redefined the concept of anesthesia emphasizing the importance of the Autonomic Nervous System changing analgesia for areflexia. Opioid-free anesthesia is based on controlling the ANS response. In this case, we can see how ANI can direct OFA, making it easy for physicians to detect nociception and improve it after. When the doctor stimulates the… View Article
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